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Remember, B12 deficiency can cause a whole host of symptoms, and reversing those effects might take some time

These limitations do not invalidate the published model studies

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[67] The World Health Organization also uses 2.4 g/day as the adult recommended nutrient intake for this vitamin

Individuals with B12 deficiency, which can occur due to dietary restrictions (e.g., vegan or vegetarian diets), gastrointestinal disorders affecting absorption, older age, or certain medical conditions that interfere with B12 absorption

MOTS-c plays a role in mitochondrial biogenesis (new cell growth) which enhances cellular energy production and overall mitochondrial function